Select one or more newsletters to continue. They are sold under the brand names Repatha and Praluent. Includes Repatha side effects, interactions and indications. The research study is a wholesome collection of primary and secondary data collected and analysed from valuable information sources. Right now, there are two FDA-approved medications: alirocumab (Praluent) and evolocumab ( Repatha ). Skip header and main navigation. GoodRx works to make its website accessible to all, including those with disabilities. The study on the global PCSK9 Inhibitors Market for all relevant companies dealing with the PCSK9 Inhibitors Market and related profiles include data in quantitative terms, product portfolio, and business strategy along with active tracking of recent developments. The PCSK9 inhibitor blocks the PCSK9 enzyme, resulting in more LDL receptors available to remove LDL from the blood, which produces in a decrease in LDL blood levels. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. To find your exact price, please contact the pharmacy (and note that the pharmacy will need to process the information shown on your coupon to confirm the price.). They are not yet licensed for use. PCSK9 inhibitors These medications offer an alternative for those who can’t take statins. They block the PCSK9 protein's ability to work, which helps the liver get rid of more bad cholesterol from … Brand names: Repatha Drug class(es): PCSK9 inhibitors Evolocumab systemic is used in the treatment of: Cardiovascular Risk Reduction; High Cholesterol; High Cholesterol, Familial Heterozygous; High Cholesterol, Familial Homozygous; See Also → Search the entire Drugs.com site for evolocumab. Repatha (evolocumab) is a PCSK9 inhibitor used to treat hypercholesterolemia (high cholesterol). It is meant to be representative but may not accurately reflect the actual # of prescriptions written to treat a specific condition. Insurance co-pays are typically less. They work by helping to reduce the amount of … EVOLOCUMAB is known as a PCSK9 inhibitor. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. GoodRx gathers prices and discounts from multiple sources, including published price lists, drug manufacturers, claims information and data provided to us by pharmacies. 6 Plasma PCSK9 concentrations are raised by statins and this could attenuate the effect of these drugs. Drug images are also included. This chart is created by aggregating the total number of claims for the drugs in this class divided by the # of drugs with a specific indication. “Part of the reason is that the body compensates by increasing levels of PCSK9,” he explains. Most of the benefit of statin treatment comes from a low dose; doubling the dose increases LDL-C reduction by only another 6%, according to Sotiris Antoniou, consultant pharmacist in cardiovascular medicine at Barts Health NHS Trust. … PCSK9 inhibitors are a new class of drugs that lower LDL, or “bad,” cholesterol. US Brand Name. Drug information provided by: IBM Micromedex. For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective). PCSK9 inhibitors are expected to work synergistically with statins. Lp(a) is not currently understood to be cleared by the LDL receptor, and statins, which upregulate the LDL receptor, do not substantially lower plasma concentrations of Lp(a). It is used to lower the level of, The GoodRx Fair Price represents the maximum price that a consumer, with or without insurance, should pay for this drug at a local pharmacy.